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1

Comparison of three different promoter systems for secretory α-amylase production in fed-batch cultures of recombinant Saccharomyces cerevisiae

Yong Soo Park, Sumihisa Shiba, Shinji lijima, Takeshi Kobayashi, Fumio Hishinuma

Journal:

Biotechnology and Bioengineering

Year:

1993

Language:

english

File:

PDF, 801 KB

english, 1993

2

Secretion of mouse α-amylase from fission yeast Schizosaccharomyces pombe: Presence of chymostatin-sensitive protease activity in the culture medium

Masao Tokunaga, Akiko Kawamura, Sayuri Yonekyu, Masao Kishida, Fumio Hishinuma

Journal:

Year:

1993

Language:

english

File:

PDF, 705 KB

english, 1993

3

Integration of heterologous genes into the chromosome ofSaccharomyces cerevisiaeusing a delta sequence of yeast retrotransposon Ty

Akira Sakai, Yuki Shimizu, Fumio Hishinuma

Journal:

Applied Microbiology and Biotechnology

Year:

1990

Language:

english

File:

PDF, 1.09 MB

english, 1990

4

Biologically active human and mouse nerve growth factors secreted by the yeastSaccharomyces cerevisiae

Masafumi Nishizawa, Fumiko Ozawa, Takako Higashizaki, Keiko Hirai, Fumio Hishinuma

Journal:

Applied Microbiology and Biotechnology

Year:

1993

Language:

english

File:

PDF, 1.67 MB

english, 1993

5

Control of gene expression from theSUC2promoter ofSaccharomyces cerevisiaewith the aid of a glucose analyser

Kong Hua Lin, Shinji Iijima, Kazuyuki Shimizu, Fumio Hishinuma, Takeshi Kobayashi

Journal:

Applied Microbiology and Biotechnology

Year:

1989

Language:

english

File:

PDF, 419 KB

english, 1989

6

Construction of yeast secretion vectors designed for production of mature proteins using the signal sequence of yeast invertase

Masafumi Nishizawa, Fumiko Ozawa, Fumio Hishinuma

Journal:

Applied Microbiology and Biotechnology

Year:

1989

Language:

english

File:

PDF, 990 KB

english, 1989

7

Genome organization of the linear plasmid, pSKL, isolated fromSaccharomyces kluyveri

Fumio Hishinuma, Keiko Hirai

Journal:

Molecular Genetics and Genomics

Year:

1991

Language:

english

File:

PDF, 1.53 MB

english, 1991

8

Evidence for preferential multiplication of the internal unit in tandem repeats of the mating factor a genes inSaccharomycesyeasts

Kunio Kitada, Fumio Hishinuma

Journal:

Current Genetics

Year:

1988

Language:

english

File:

PDF, 466 KB

english, 1988

9

A new linear DNA plasmid isolated from the yeastSaccharomyces kluyveri

Kunio Kitada, Fumio Hishinuma

Journal:

Molecular Genetics and Genomics

Year:

1987

Language:

english

File:

PDF, 466 KB

english, 1987

10

Terminal segment ofKluyveromyces lactislinear DNA plasmid pGKL2 supports autonomou sreplication of hybrid plasmids inSaccharomyces cerevisiae

Hiro-aki Fujimura, Fumio Hishinuma, Norio Gunge

Journal:

Current Genetics

Year:

1987

Language:

english

File:

PDF, 505 KB

english, 1987

11

Mitosis and mitotic wave propagation in the coenocytic alga,Vaucheria terrestrissensu Goetz

Fumio Takahashi, Koji Yamaguchi, Tasuku Hishinuma, Hironao Kataoka

Journal:

Journal of Plant Research

Year:

2003

Language:

english

File:

PDF, 468 KB

english, 2003

12

DNA replication in vivo of linear DNA killer plasmids pGKL1 and pGKL2 in Saccharomyces cerevisiae

Hiro-aki Fujimura, Takashi Yamada, Fumio Hishinuma, Norio Gunge

Journal:

FEMS Microbiology Letters

Year:

1988

Language:

english

File:

PDF, 459 KB

english, 1988

13

Purification and determination of the NH2-terminal amino acid sequence of mouse α-amylase secreted from Saccharomyces cerevisiae: correct processing of the secretion signal from pGKL killer 28 kDa precursor protein

Masao Tokunaga, Akiko Kawamura, Akira Omori, Fumio Hishinuma

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1991

Language:

english

File:

PDF, 499 KB

english, 1991

14

Optimization of the expression of a foreign gene from galactose-inducible promoter in a recombinant yeast

Kong Hua Lin, Shinji Iijima, Shih-yow Huang, Fumio Hishinuma, Takeshi Kobayashi

Journal:

Journal of Fermentation and Bioengineering

Year:

1991

Language:

english

File:

PDF, 669 KB

english, 1991

15

Elevation of the Thromboxane A2/Prostacyclin Ratio in Urine of Diabetic Mice Analyzed by Gas Chromatography/Selected Ion Monitoring

Takanori Hishinuma, Yuko Koseki, Yuriko Murai, J Kotake, Fumio Ishii, Ken-ichi Suzuki, Michinao Mizugaki

Journal:

Prostaglandins and Other Lipid Mediators

Year:

1998

Language:

english

File:

PDF, 296 KB

english, 1998

16

Thermophilic Polynucleotide Phosphorylase from Thermus thermophilus : Purification and Properties of an Altered Form of Enzyme which Lacks Phosphorolytic Activity to Polynucleotide

Fumio HISHINUMA, Keiko HIRAI, Kenji SAKAGUCHI

Journal:

Year:

1977

Language:

english

File:

PDF, 774 KB

english, 1977

17

Structure of yeast pGKL 128-kDa killer-toxin secretion signal sequence : Processing of the 128-kDa killer-toxin-secretion-signal - α-amylase fusion protein

Masao TOKUNAGA, Akiko KAWAMURA, Akira OMORI, Fumio HISHINUMA

Journal:

Year:

1992

Language:

english

File:

PDF, 897 KB

english, 1992

18

An efficient synthesis of polyguanylic acid by a thermophilic polynucleotide phosphorylase

Yo Kikuchi, Keiko Hirai, Fumio Hishinuma, Kenji Sakaguchi

Journal:

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis

Year:

1977

Language:

english

File:

PDF, 450 KB

english, 1977

19

Expression of β-nerve growth factor mRNA in rat glioma cells and astrocytes from rat brain

Tohru Yamakuni, Fumiko Ozawa, Fumio Hishinuma, Ryozo Kuwano, Yasuo Takahashi, Takehiko Amano

Journal:

Year:

1987

Language:

english

File:

PDF, 303 KB

english, 1987

20

Cloning of a glycine receptor subtype expressed in rat brain and spinal cord during a specific period of neuronal development

Hiroyuki Akagi, Keiko Hirai, Fumio Hishinuma

Journal:

Year:

1991

Language:

english

File:

PDF, 1.05 MB

english, 1991

21

Increase in activin βA mRNA in rat hippocampus during long-term potentiation

Kaoru Inokuchi, Akihiko Kato, Keiko Hiraia, Fumio Hishinuma, Maki Inoue, Fumiko Ozawa

Journal:

Year:

1996

Language:

english

File:

PDF, 1.05 MB

english, 1996

22

A novel yeast secretion vector utilizing secretion signal of killer toxin encoded on the yeast linear DNA plasmid pGKL1

Masao Tokunaga, Naomi Wada, Fumio Hishinuma

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 728 KB

english, 1987

23

Synthesis and secretion of human nerve growth factor by Saccharomyces cerevisiae

Kanaya Eiko, Higashizaki Takako, Ozawa Fumiko, Hirai Keiko, Nishizawa Masafumi, Tokiinaga Masao, Tsukui Hiroko, Hatanaka Hiroshi, Hishinuma Fumio

Journal:

Year:

1989

Language:

english

File:

PDF, 1.67 MB

english, 1989

24

Enhanced Secretion of Human Nerve Growth Factor from Saccharomyces cerevisiae using an Advanced δ–Integration System

Sakai, Akira, Ozawa, Fumiko, Higashizaki, Takako, Shimizu, Yuki, Hishinuma, Fumio

Journal:

Year:

1991

File:

PDF, 857 KB

1991

25

Down-regulation of glycine receptor channels by protein kinase C in Xenopus oocytes injected with synthetic RNA

Mutsumi Uchiyama, Keiko Hirai, Fumio Hishinuma, Hiroyuki Akagi

Journal:

Molecular Brain Research

Year:

1994

Language:

english

File:

PDF, 573 KB

english, 1994

26

Gene Expression Analysis Using a High-Resolution DNA Microarray of Peripheral Whole Blood Immediately Before and After Leukocytapheresis for Rheumatoid Arthritis

Kusaoi, Makio, Yamaji, Ken, Murayama, Go, Yasui, Misa, Yamada, Risa, Hishinuma, Ruka, Nemoto, Takuya, Hohtatsu, Katsura, Kageyama, Michiaki, Kawamoto, Toshio, Sugimoto, Kaoru, Sekiya, Fumio, Kon, Taka

Journal:

Therapeutic Apheresis and Dialysis

Year:

2012

Language:

english

File:

PDF, 1.85 MB

english, 2012

27

Tissue-specific expression of two mRNA variants encoding glycine receptor subunit α2 in rat brain and spinal cord

Akagi, Hiroyuki, Hirai, Keiko, Hishinuma, Fumio

Journal:

Neuroscience Research Supplements

Year:

1991

Language:

english

File:

PDF, 118 KB

english, 1991

28

Estrogen can regulate the cell cycle in the early G1 phase of yeast by increasing the amount of adenylate cyclase mRNA

Tanaka, Shigeo, Hasegawa, Satoshi, Hishinuma, Fumio, Kurata, Shun-ichi

Journal:

Year:

1989

Language:

english

File:

PDF, 780 KB

english, 1989

29

The distribution of [11C]cocaine in normal and cocaine-sensitization mice

Mizugaki, Michinao, Hishinuma, Takanori, Kimura, Katsuhiko, Nakamura, Hitoshi, Aso, Hisashi, Ishii, Fumio, Nishikawa, Masazumi, Itoh, Kunihiko, Tomioka, Yoshihisa, Ishiwata, Shunji, Moritani, Hiroshi,

Journal:

Nuclear Medicine and Biology

Year:

1994

Language:

english

File:

PDF, 605 KB

english, 1994

30

325 Extracellular zinc ion increases cl− currents generated through cloned glycine receptor channels expressed in Xenopus oocytes

Akagi, Hiroyuki, Majima, Takehiko, Hirai, Keiko, Hishinuma, Fumio

Journal:

Neuroscience Research Supplements

Year:

1993

Language:

english

File:

PDF, 102 KB

english, 1993

31

Depression by a phorbol ester of Cl− currents generated through cloned glycine receptors

Uchiyama, Matsumi, Akagi, Hiroyuki, Hirai, Keiko, Hishinuma, Fumio

Journal:

Neuroscience Research Supplements

Year:

1992

Language:

english

File:

PDF, 112 KB

english, 1992

32

Regulation of nerve growth factor and nerve growth factor receptor production by NMDA in C6 glioma cells

Amano, Takehiko, Yamakuni, Tohru, Okabe, Noriko, Kuwahara, Reiko, Ozawa, Fumiko, Hishinuma, Fumio

Journal:

Molecular Brain Research

Year:

1992

Language:

english

File:

PDF, 603 KB

english, 1992

33

Control of tryptophan synthetase amplified by varying the numbers of composite plasmids in Escherichia coli cells

Nagahari, Kenji, Tanaka, Teruo, Hishinuma, Fumio, Kuroda, Motoko, Sakaguchi, Kenji

Journal:

Year:

1977

Language:

english

File:

PDF, 1.37 MB

english, 1977

34

Functional correlation of fetal and adult forms of glycine receptors with developmental changes in inhibitory synaptic receptor channels

Takahashi, Tomoyuki, Momiyama, Akiko, Hirai, Keiko, Hishinuma, Fumio, Akagi, Hiroyuki

Journal:

Year:

1992

Language:

english

File:

PDF, 1.31 MB

english, 1992

35

Functional properties of cloned and its mutant glycine receptors consisting of single subunit examined in Xenopus oocytes

Akagi, Hiroyuki, Hirai, Keiko, Hishinuma, Fumio

Journal:

Neuroscience Research Supplements

Year:

1991

Language:

english

File:

PDF, 104 KB

english, 1991

36

Addition of Mononucleotides to Oligoribonucleotide Acceptors with T4 RNA ligase

Yo Kikuchi, Fumio Hishinuma and Kenji Sakaguchi

Journal:

Proceedings of the National Academy of Sciences

Year:

1978

Language:

english

File:

PDF, 654 KB

english, 1978

37

Characterization of IKI1 and IKI3 Genes Conferring pGKL Killer Sensitivity on Saccharomyces cerevisiae

Yajima, Hirohiko, Tokunaga, Masao, Nakayama-Murayama, Akiko, Hishinuma, Fumio

Journal:

Bioscience Biotechnology and Biochemistry

Year:

1997

Language:

english

File:

PDF, 1.22 MB

english, 1997

38

Isolation and Genetic Characterization of pGKL Killer-insensitive Mutants (iki) from Saccharomyces cerevisiae

Kishida, Masao, Tokunaga, Masao, Katayose, Yuichi, Yajima, Hirohiko, Kawamura-Watabe, Akiko, Hishinuma, Fumio

Journal:

Bioscience Biotechnology and Biochemistry

Year:

1996

Language:

english

File:

PDF, 727 KB

english, 1996

39

Reduction in bradykinin generation during leukocytapheresis using novel cellsorba TM CS-180S: Effects of changing the filling solution

Yamada, Risa, Kusaoi, Makio, Murayama, Go, Yasui, Misa, Hishinuma, Ruka, Nemoto, Takuya, Hohtatsu, Katsura, Kageyama, Michiaki, Kawamoto, Toshio, Sugimoto, Kaoru, Sekiya, Fumio, Kon, Takayuki, Ogasawa

Journal:

Journal of Clinical Apheresis

Year:

2014

Language:

english

File:

PDF, 242 KB

english, 2014

40

Molecular Cloning of an Amylase Gene of Bacillus circulans

NISHIZAWA, MASAFUMI, OZAWA, FUMIKO, HISHINUMA, FUMIO

Journal:

Year:

1987

Language:

english

File:

PDF, 2.52 MB

english, 1987

41

The yeast linear DNA killer plasmids, pGKL1 and pGKL2, possess terminally attached proteins

Kikuchi, Yo, Hirai, Keiko, Hishinuma, Fumio

Journal:

Nucleic Acids Research

Year:

1984

Language:

english

File:

PDF, 2.66 MB

english, 1984

42

Molecular analysis of POP2 gene, a gene required for glucose-derepression of gene expression in Saccharomyces cerevisiae

Sakai, Akira, Chibazakura, Taku, Shimizu, Yuki, Hishinuma, Fumio

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 2.41 MB

english, 1992

43

Sequence-directed bends of DNA helix axis at the upstream activation sites of α-cell-specific genes in yeast

Inokuchi, Kaoru, Nakayama, Akiko, Hishinuma, Fumio

Journal:

Nucleic Acids Research

Year:

1988

Language:

english

File:

PDF, 953 KB

english, 1988

44

A novel yeast secretion signal isolated from 28K killer precursor protein encoded on the linear DNA plasmid pGKL1

Tokunaga, Masao, Wada, Naomi, Hishinuma, Fumio

Journal:

Nucleic Acids Research

Year:

1988

Language:

english

File:

PDF, 991 KB

english, 1988

45

Expression of pGKL killer 28K subunit in Saccharomyces cerevisiae : identification of 28K subunit as a killer protein

Tokunaga, Masao, Kawamura, Akiko, Hishinuma, Fumio

Journal:

Nucleic Acids Research

Year:

1989

Language:

english

File:

PDF, 3.22 MB

english, 1989

46

Effects of Glycine and d -Amino Acids on Growth of Various Microorganisms

Hishinuma, Fumio, Izaki, Kazuo, Takahashi, Hajime

Journal:

Agricultural and Biological Chemistry

Year:

1969

Language:

english

File:

PDF, 694 KB

english, 1969

47

Ruminal Fermentation and Sugar Concentrations

Hishinuma, Fumio, Kanegasaki, Shiro, Takahashi, Hajime

Journal:

Agricultural and Biological Chemistry

Year:

1968

Language:

english

File:

PDF, 534 KB

english, 1968

48

Characterization of Mouse α -Amylase Secreted from Saccharomyces cerevisiae by the pGKL 128 kDa Killer Secretion Signal

Tokunaga, Masao, Kawamura, Akiko, Omori, Akira, Hishinuma, Fumio

Journal:

Bioscience Biotechnology and Biochemistry

Year:

1992

Language:

english

File:

PDF, 680 KB

english, 1992

49

Inhibition of l -Alanine Adding Enzyme by Glycine

Hishinuma, Fumio, Izaki, Kazuo, Takahashi, Hajime

Journal:

Agricultural and Biological Chemistry

Year:

1971

Language:

english

File:

PDF, 768 KB

english, 1971

50

The Design and Performance of a PEFC at a Temperature Below Freezing

HISHINUMA, Yukio, CHIKAHISA, Takemi, KAGAMI, Fumio, OGAWA, Tomohiro

Journal:

JSME International Journal Series B

Year:

2004

Language:

english

File:

PDF, 1.74 MB

english, 2004